Practice at home and abroad has proven that sodium humate is not only a good biological growth hormone, but also a widely used drug.
For example: due to the large molecular weight of humic acid itself, it can associate into larger particles in a certain medium, so it has colloidal properties and adsorption capacity. There are many phenolic hydroxyl groups on the humic acid nanomolecules, so it has weak alkalinity and strong Ion exchange ability, chelating ability and buffering ability, the phenolic quinone structure on the sodium humate molecule can participate in the electron transfer system of biological redox. These physical and chemical characteristics may also affect the function of biological macromolecules, resulting in physiological, Pharmacological activity.
We studied the effects of sodium humate on gastrointestinal motility and gastric ulcers in animals. Using black carbon powder as an indicator, we measured the inhibition of small intestinal propulsion in normal animals, animals caused by compound diphenol, and diarrhea caused by spleen deficiency in animals caused by sodium humate. The percentage of charcoal powder advancement in the model, the effect of sodium humate on intestinal motility of animals, the use of absolute ethanol gavage to cause acute gastric ulcers in animals, the protective effect of preventive administration of sodium humate on gastric mucosal damage, the calculation of ulcer index and ulcer Inhibition rate. Sodium humate has a certain inhibitory effect on gastrointestinal motility in normal animals and animal diarrhea models caused by raw rhubarb. It has a significant synergistic effect on the weakening of gastrointestinal motility in animals caused by compound diphenol, and on gastric mucosal damage in animals caused by absolute ethanol. It has a protective effect. There is no significant difference in the ulcer index and ulcer inhibition rate between high-dose sodium humate and the positive control ranitidine.
The results show that within the dose range, humic acid has very little acute toxicity and has anti-diarrheal, anti-gastric ulcer, and protective gastric mucosa effects.
Practical application shows that sodium humate has obvious effects in the fields of veterinary medicine and veterinary medicine.